The artificial intelligence industry’s data center boom is the latest chapter in a long history of environmental racism and resource exploitation in vulnerable Native communities, says Oglala Lakota and Northern Cheyenne activist Krystal Two Bulls, the executive director of Honor the Earth, an Indigenous-led environmental justice organization that is tracking over 100 proposed data center projects on tribal and rural lands. We speak to Two Bulls about the myriad impacts of what she calls a “modern-day iteration” of “settler colonialism,” including noise pollution, cancers and respiratory illnesses, water depletion, energy grid overload and even “ecological collapse.” As tech companies set their sights on Indigenous lands, Two Bulls says, “We’re always the one that ends up having to sacrifice our relationship to land, air, water, our communities and our nonhuman relatives.”